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Pittsburgh Steelers CB Jalen Ramsey (hamstring) is expected to play in Week 6's game versus the Cleveland Browns, after his status on the injury report was upgraded from questionable Saturday, Oct. 11.
The Indianapolis Colts elevated RB Ameer Abdullah from the practice squad to the active roster Saturday, Oct. 11, for Week 6's game against the Arizona Cardinals.
Tampa Bay Buccaneers WR Jalen McMillan (neck) is hopeful that he can return to action this year, according to head coach Todd Bowles. He is currently using a neck brace and is on the Reserve/Injured list after he sustained a sprained neck during the preseason.
Detroit Lions Ss Brian Branch (ankle) and Kerby Joseph (knee) will be game-time decisions for Week 6's game versus the Kansas City Chiefs, after neither player took part in practice Friday, Oct. 10, according to head coach Dan Campbell. Branch and Joseph are both listed as questionable on the injury report.
Jacksonville Jaguars CB Greg Newsome II is expected to make his debut with the club in Week 6's game versus the Seattle Seahawks, according to head coach Liam Coen. Newsome had been acquired from the Cleveland Browns in a trade earlier this week.
Updating previous reports, Indianapolis Colts WR Alec Pierce will play in Week 6's game against the Arizona Cardinals after clearing concussion protocol, according to head coach Shane Steichen.
Tennessee Titans DT T'Vondre Sweat (ankle), who is currently on the Reserve/Injured list, will have his 21-day practice window opened next week, according to head coach Brian Callahan.
The Seattle Seahawks re-signed free-agent WR Cody White (Seahawks) to their practice squad Friday, Oct. 10.
Updating a previous report, Indianapolis Colts LB Joe Bachie (foot) has not been ruled out for the 2025 season despite being placed on the Reserve/Injured list earlier this week, according to head coach Shane Steichen.
New Orleans Saints WR Chris Olave's 54 targets entering Week 6 are the second most in the NFL, and Olave has been targeted at least 10 times in four of his five games.
Los Angeles Rams QB Matthew Stafford faces the Baltimore Ravens in Week 6, and the Ravens are allowing the second-most passing yards per game and have surrendered a league-high 13 touchdown passes.
Carolina Panthers WR Tetairoa McMillan faces the Dallas Cowboys in Week 6, and the Cowboys are allowing the most passing yards per game and have given up the second-most touchdown passes.
Cincinnati Bengals WR Ja'Marr Chase (illness), who is listed as questionable for the Week 6 game against the Green Bay Packers, is expected to play, according to sources.
Free-agent DE K.J. Henry (Eagles) is being signed to the Pittsburgh Steelers' practice squad Friday, Oct. 10.
Tampa Bay Buccaneers WR Chris Godwin (fibula) did not participate in practice Friday, Oct. 10, and has been ruled out for Week 6.
San Francisco 49ers WR Jauan Jennings (ankle, rib) was limited during practice Friday, Oct. 10, and is listed as questionable for Week 6.
San Francisco 49ers WR Kendrick Bourne (rib) fully participated in practice Friday, Oct. 10, and is not on the injury report for Week 6.
San Francisco 49ers WR Ricky Pearsall (knee) did not participate in practice Friday, Oct. 10, and has been ruled out for Week 6.
San Francisco 49ers RB Christian McCaffrey (non-injury) fully participated in practice Friday, Oct. 10, and is not on the injury report for Week 6.
San Francisco 49ers QB Mac Jones (knee, oblique) was limited during practice Friday, Oct. 10, and is listed as questionable for Week 6.

Free-agent QB Seth Henigan (Jaguars), WR Colton Dowell (Titans) and WR Chris Tyree (Saints) recently worked out for the Baltimore Ravens.
New England Patriots RB Antonio Gibson (knee) was placed on the Reserve/Injured list Friday, Oct. 10.

Carolina Panthers WR Dalevon Campbell (hamstring) was waived from the Reserve/Injured list Friday, Oct. 10.
San Francisco 49ers QB Brock Purdy (toe) did not participate in practice Friday, Oct. 10, and has been ruled out for Week 6.