San Francisco 49ers OG Spencer Burford (knee) and WR Jordan Watkins (calf) did not participate in practice Friday, Sept. 19, and have been ruled out for Week 3. WR Jauan Jennings (ankle, shoulder) did not practice and is listed as questionable. OG Connor Colby (groin) and QB Brock Purdy (shoulder, toe) were limited during practice and are listed as questionable. DE Yetur Gross-Matos (knee) did not practice but is not on the injury report. DE Nick Bosa (non-injury), RB Jordan James (finger), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) fully participated in practice and are not on the injury report.
ESPN.com - Josh Weinfuss