San Francisco 49ers DE Robert Beal Jr. (ankle), OG Spencer Burford (calf), CB Deommodore Lenoir (shoulder), QB Brock Purdy (elbow) and WR Deebo Samuel (rib, wrist) did not take part in practice on Friday, Jan. 3, and were ruled out for Week 18. Also, LB Demetrius Flannigan-Fowles (calf) did not practice and is doubtful, TE George Kittle (ankle, hamstring), OT Colton McKivitz (knee), CB Isaac Yiadom (pelvis) and S Ji’Ayir Brown (ankle) were limited and are questionable and DE Nick Bosa (knee), DE Leonard Floyd (shoulder), WR Ricky Pearsall (illness, chest), RB Isaac Guerendo (foot, hamstring) and S Talanoa Hufanga (wrist) practiced in full and were removed from the injury report.
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