San Francisco 49ers RB Tevin Coleman (non-injury) was held out of practice Friday, Sept. 11, due to a pre-existing condition (sickle-cell trait), and head coach Kyle Shanahan told reporters that it will be up to Coleman if he wants to play in Week 1 against the Arizona Cardinals if the AQI (Air Quality Index) continues to hover around 150.
ESPN.com - Nick Wagoner